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Generic TopamaxAnti Convulsants / Generic Topamax
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Topiramate is used for:

  • Treating certain kinds of seizures in patients 2 years of age or older. It is also prescribed to prevent migraine headache in adults.
  • Topiramate is a carbonic anhydrase inhibitor. It works by controlling nerve impulses in the brain.

Do NOT use Topiramate if:

    • you are allergic to any ingredient in Topiramate
    • you are taking other carbonic anhydrase inhibitors (eg, acetazolamide)
  • Contact your doctor or health care provider right away if any of these apply to you.

Before using Topiramate :

    • Some medical conditions may interact with Topiramate . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:
      • if you are pregnant, plan to become pregnant, or are breast-feeding
      • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
      • if you have allergies to medicines, foods, or other substances
      • if you have liver or kidney problems, kidney stones, or regularly consume alcohol
      • if you have diarrhea, a respiratory tract disease, or you are scheduled for surgery
      • if you have status epilepticus (continuous seizure activity or a series of seizures without a full return to consciousness)
      • if you are on a diet that increases the amount of ketones in your blood and results in fruity-smelling breath
    • Some MEDICINES MAY INTERACT with Topiramate . Tell your health care provider if you are taking any other medicines, especially any of the following:
      • Carbamazepine or hydantoins (eg, phenytoin) because the effectiveness of Topiramate may be decreased
      • Amitriptyline, carbamazepine, hydantoins (eg, phenytoin), or metformin because the actions and side effects of these medicines may be increased
      • Risperidone because its effectiveness may be decreased by Topiramate
    • This may not be a complete list of all interactions that may occur. Ask your health care provider if Topiramate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    How to use Topiramate :

    • Use Topiramate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
      • Topiramate may be taken with or without food.
      • Drink plenty of fluids while taking Topiramate to prevent kidney stones from forming.
      • Swallow Topiramate whole. Do not crush, break, or chew before swallowing.
      • Suddenly stopping Topiramate may cause seizures to occur more often. Stopping therapy should be gradual.
      • If you miss a dose of Topiramate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
    • Ask your health care provider any questions you may have about how to use Topiramate .

    Important safety information:

    • Topiramate may cause dizziness, drowsiness, confusion, difficulty concentrating, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Topiramate . Using Topiramate alone, with other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
    • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Topiramate . Topiramate will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
    • Topiramate may reduce sweating, which could raise body temperature, especially in children. The risk of this serious side effect is greater in hot weather and/or during vigorous exercise. Drink plenty of fluids and dress lightly while in hot climates or when exercising. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. Seek immediate medical attention if your body temperature is above normal, or if you have mental or mood changes, headache, or dizziness.
    • Additional monitoring of your dose or condition may be needed if you are taking other medicines that reduce sweating. These medicines include anticholinergics (eg, benztropine), amitriptyline, haloperidol, or carbonic anhydrase inhibitors (eg, acetazolamide).
    • Topiramate may result in a change in the acidity (pH) of your blood. If you experience loss of appetite, changes in breathing, tiredness, or change in heart rhythm, contact your health care provider.
    • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are taking Topiramate .
    • Topiramate may decrease the effectiveness of your birth control pill. To prevent pregnancy, be sure to use an additional form of birth control while using Topiramate .
    • Diabetic patients - Topiramate may alter blood sugar levels in patients taking metformin. Check your blood sugars more frequently and contact your doctor for dose changes.
    • LAB TESTS, such as serum bicarbonate, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
    • Topiramate is not recommended for use in CHILDREN under the age of 2 years; safety and effectiveness in this age group have not been confirmed.
    • . PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Topiramate during pregnancy. Topiramate is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the risks to your baby.

    Possible side effects of Topiramate :

    • All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
      • Abnormal skin sensations (numbness or tingling, decreased sensitivity)
      • abnormal walking
      • agitation or aggression
      • appetite loss
      • back pain
      • breast pain
      • change in speech
      • clumsiness
      • coordination decreased
      • confusion
      • constipation
      • decreased hearing
      • decreased sweating
      • depression
      • diarrhea
      • difficulty with concentration or attention
      • dizziness
      • drowsiness
      • dry mouth
      • fatigue
      • flu-like symptoms
      • hot flushes
      • injury
      • indigestion
      • infection
      • itching
      • leg pain;menstrual disorder;mood swings
      • muscle pain or contractions
      • nausea
      • nervousness or anxiety
      • runny nose
      • saliva increased
      • sex drive decreased
      • sinus swelling
      • skin disorder
      • stomach pain or ache
      • strange taste
      • sore throat
      • thinking problems
      • thirst
      • tremor
      • unstable emotions
      • vomiting
      • weakness.
    • Seek medical attention right away if any of these SEVERE side effects occur:
      • Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
      • blood in the urine
      • blurred vision or sudden worsening of vision
      • chest pain
      • difficulty concentrating
      • fast, deep breathing
      • feeling of moving slowly
      • increased body temperature
      • irregular heartbeat
      • loss of consciousness
      • memory problems
      • painful/red eyes;prostate problems;severe stomach pain
      • significant weight loss
      • speech problems
      • stupor
      • unexplained fever
      • unusual eye movements
      • unusual tiredness
      • urinary incontinence
      • urinary tract infection.

    What is the shelf life of the pills?

    • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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