Does a generic medication differ from a brand name drug?
Not much, actually. But there is a difference, of course. To see the difference more clearly we have made a table: click here
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Ribavirin is used for:
Treating hepatitis C infection in certain patients when used in combination with interferon. It may also be used for other conditions as determined by your doctor.
Ribavirin is an antiviral medicine. How Ribavirin works to treat hepatitis C is not completely understood.
Do NOT use Ribavirin if:
you are pregnant
your female sexual partner is pregnant or could become pregnant within the next 6 months
you have certain blood disorders (eg, sickle-cell anemia, thalassemia major), a history of serious heart problems, severe kidney problems, or inflammation of your pancreas (acute pancreatitis)
you are also using interferon and have autoimmune hepatitis (liver problems caused by your own body instead of a virus) or severely decreased liver function
you are taking didanosine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Ribavirin :
Some medical conditions may interact with Ribavirin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you plan to become pregnant or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a female sexual partner who is of childbearing age
if you have a history of cancer, heart problems or heart attack, high blood pressure, kidney problems, diabetes, pancreas problems, lung or breathing problems, sarcoidosis, blood problems (eg, anemia), thyroid problems, or HIV infection
if you have liver problems (other than hepatitis C infection) such as hepatitis B infection, cirrhosis of the liver, or decreased liver function
if you have a history of anxiety or other mood or mental disorders, thoughts of suicide, or suicidal behavior
if you have used interferon before to treat hepatitis C and it did not work
if you have a history of drug or alcohol abuse
Some MEDICINES MAY INTERACT with Ribavirin. Tell your health care provider if you are taking any other medicines, especially any of the following:
Didanosine or other nucleoside reverse transcriptase inhibitors (NRTIs) (eg, lamivudine), immunosuppressants (eg, cyclosporine), or other antiretroviral medicines for HIV infection because serious side effects, including risk of infection, nerve problems (peripheral neuropathy),
pancreas problems, lactic acidosis, and severe or fatal liver failure, may
be increased by Ribavirin
Anticoagulants (eg, warfarin) because the effectiveness of Ribavirin may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Ribavirin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Ribavirin :
Use Ribavirin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ribavirin comes with an additional patient information sheet called a Medication Guide. Read it carefully and reread it each time you get Ribavirin refilled.
Ribavirin should be taken with food.
Drinking extra fluids while you are taking Ribavirin is recommended. Check with your doctor for instructions.
Take Ribavirin regularly to receive the most benefit from it. Taking Ribavirin at the same times each day will help you remember to take it.
Continue to use Ribavirin even if you feel well. Do not miss any doses.
If you miss a dose of Ribavirin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Ribavirin.
Important safety information:
Ribavirin may cause dizziness, drowsiness, tiredness, confusion, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Ribavirin. Using Ribavirin alone, with certain other medicines, or with alcohol may lessen your ability to drive
or perform other potentially dangerous tasks.
Avoid drinking alcohol, including beer, wine, and liquor, because it could worsen liver disease.
LAB TESTS, including pregnancy tests; blood counts; hemoglobin levels; and heart, liver, kidney, thyroid, and lung function tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
At least 2 reliable forms of effective birth control must be used during treatment with Ribavirin and for 6 months after treatment with Ribavirin is stopped.
Women of childbearing potential who either take Ribavirin or are sexual partners of men who take Ribavirin must have a pregnancy test before therapy with Ribavirin is started, monthly during therapy, and monthly for 6 months after Ribavirin is stopped.
Caution is advised when using Ribavirin in CHILDREN because they may be more sensitive to its effects.
Use Ribavirin with caution in the ELDERLY because they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: Do not use Ribavirin if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if Ribavirin is excreted in breast milk. Do not breast-feed while taking Ribavirin.
Possible side effects of Ribavirin :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Cough; diarrhea; dizziness; dry mouth; dry skin; loss of appetite; mild headache, nausea, or vomiting; mild pain, redness, or swelling at the injection site; tiredness; upset stomach; weakness or fatigue
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; itching; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in hearing, taste, or vision; chest pain; dark urine; decrease in the amount of urine; fever, chills, or sore throat; hair loss; irregular heartbeat; joint pain; loss of appetite;
muscle pain or weakness; numbness or tingling of arms or legs; prolonged nausea
and vomiting; rapid breathing; severe headache; severe stomach or back pain;
shortness of breath; sinus problems; thoughts of suicide; trouble sleeping;
unusual bruising or bleeding; unusual mental or mood changes; unusual or severe
tiredness and fatigue; vomit that looks like coffee grounds; weight loss;
yellowing of eyes or skin.
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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Erectile dysfunction
Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.
Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.
This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.
What is Erectile Dysfunction?
Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.
The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.
Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.
The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.
Signs and symptoms:
Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).
Here are some causes of Erectile Dysfunction:
* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.
* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.
* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.
Physiology of normal erections:
Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.
Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.
Pathophysiology of erectile dysfunction:
Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.
Treatment:
Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.
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