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Repaglinide is used for:
Managing type 2 (non-insulin-dependent) diabetes. It is used in addition to diet and exercise to lower blood sugar in adults who cannot manage with diet, exercise, or diabetic medications alone. It may be used with other diabetes medicines.
Repaglinide is a meglitinide antidiabetic. It works to lower blood glucose (sugar) by stimulating the release of insulin from the pancreas gland. Repaglinide does not work in type 1 (insulin-dependent) diabetes, because in this condition the pancreas gland is not capable of making or releasing insulin.
Do NOT use Repaglinide if:
you are allergic to any ingredient in Repaglinide
you have type 1 diabetes (insulin-dependent diabetes) or have elevated ketone levels due to diabetes
you are also taking gemfibrozil
Contact your doctor or health care provider right away if any of these apply to you.
Before using Repaglinide :
Some medical conditions may interact with Repaglinide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription medicine, nonprescription medicine, herbal preparation or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of acidosis, kidney disease, or liver disease
Some MEDICINES MAY INTERACT with Repaglinide. Tell your health care provider if you are taking any other medicines, especially any of the following:
Rifampin because the effectiveness of Repaglinide may be decreased
Beta blockers (eg, propranolol), gemfibrozil, imidazoles (eg, ketoconazole), macrolides and ketolides (eg, erythromycin, azithromycin), monoamine oxidase (MAO) inhibitors (eg, phenelzine), quinolones (eg, ciprofloxacin), or salicylates (eg, aspirin) because side effects, such as low blood sugar,
may be increased
Insulin because it may increase the risk of side effects of Repaglinide
This may not be a complete list of all interactions that may occur. Ask your health care provider if Repaglinide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Repaglinide :
Use Repaglinide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Repaglinide 15 to 30 minutes before each meal. If you skip a meal, do not take the dose for the skipped meal. If you add an extra meal, take an extra dose with that meal.
If you miss a dose of Repaglinide , skip the missed dose and go back to your regular dosing schedule.
Ask your health care provider any questions you may have about how to use Repaglinide.
Important safety information:
Fever, injury, infection, or surgery may affect your diabetes control. If any of these occur, check with your doctor.
Diabetes patients - Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor’s directions. If your blood sugar level is often higher than it should be and you are taking Repaglinide according to directions, check
with your doctor.
Diabetes patients - Repaglinide may cause low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, or fainting). It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you do
not have a reliable source of glucose available, eat a quick source of
sugar such as table sugar, honey, or candy, or drink a glass of orange
juice or non-diet soda to quickly raise your blood sugar level. Tell your
doctor immediately about the reaction. To prevent hypoglycemia, eat meals
on a regular schedule and do not skip meals.
Carefully follow the diet and exercise program prescribed by your health care provider.
Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Repaglinide.
LAB TESTS, such as liver and kidney function tests, fasting blood sugar, glycosylated hemoglobin, or complete blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab test appointments.
PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Repaglinide during pregnancy. It is unknown if Repaglinide is excreted in breast milk. Do not breast-feed while you are taking Repaglinide.
Possible side effects of Repaglinide :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Changes in vision; diarrhea; headache; increased heartbeat; increased hunger; joint or back pain; nasal or chest congestion; nervousness; sinus inflammation; sweating; tiredness; tremor.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain.
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
Just to inform you that your package was received Friday 27 th October
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Erectile dysfunction
Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.
Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.
This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.
What is Erectile Dysfunction?
Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.
The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.
Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.
The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.
Signs and symptoms:
Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).
Here are some causes of Erectile Dysfunction:
* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.
* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.
* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.
Physiology of normal erections:
Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.
Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.
Pathophysiology of erectile dysfunction:
Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.
Treatment:
Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.
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