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What is amlodipine?
Amlodipine is in a class of drugs called calcium channel blockers. Amlodipine relaxes (widens) the blood vessels (veins and arteries), making it easier for the heart to pump and reducing its workload.
Amlodipine is used to treat hypertension (high blood pressure) and to treat angina (chest pain).
Amlodipine may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about amlodipine?
Do not stop taking amlodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.
What should I discuss with my doctor before taking amlodipine?
Before taking amlodipine, tell your doctor if you have
liver disease; or
another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.
You may not be able to take amlodipine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Amlodipine is in the FDA pregnancy category C. This means that it is not known whether amlodipine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether amlodipine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
If you are over 65 years of age, you may be more likely to experience side effects from amlodipine. Your doctor may prescribe a lower dose of this medication.
How should I take amlodipine?
Take amlodipine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Do not stop taking amlodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.
Store amlodipine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of an amlodipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, unusually fast or slow heartbeat, coma, slurred speech, and confusion.
What should I avoid while taking amlodipine?
Follow any recommendations your doctor makes about diet or exercise.
Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions.
Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking amlodipine.
What are the possible side effects of amlodipine?
If you experience any of the following serious side effects, stop taking amlodipine and contact your doctor immediately or seek emergency medical treatment:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
unusually fast or slow heartbeat;
chest pain;
severe dizziness or fainting;
psychosis;
jaundice (yellowing of the skin or eyes); or
swelling of the legs or ankles.
Other, less serious side effects may be more likely to occur. Continue to take amlodipine and talk to your doctor if you experience
fatigue or tiredness;
headache;
insomnia;
vivid or abnormal dreams;
flushing;
abdominal pain;
nausea, diarrhea, or constipation; or
increased or difficult urination.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What drug(s) may interact with amlodipine?
antiinflammatory drugs (NSAIDs, such as ibuprofen)
barbiturates such as phenobarbital
bosentan
grapefruit juice
herbal or dietary supplements such as ginger, gingko biloba, ginseng, hawthorn, ma huang (ephedra), melatonin, St. John's wort, went yeast
imatinib, STI-571
local anesthetics or general anesthetics
medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole)
medicines for high blood pressure
medicines for HIV infection or AIDS
medicines for prostate problems
medicines for seizures (carbamazepine, phenobarbital, phenytoin, primidone, zonisamide)
rifampin, rifapentine, or rifabutin
some antibiotics (clarithromycin, erythromycin, telithromycin, troleandomycin)
some medicines for heart-rhythm problems (amiodarone, diltiazem, verapamil)
some medicines for depression or mental problems (fluoxetine, fluvoxamine, nefazodone)
water pills (diuretics)
yohimbine
zafirlukast
zileuton
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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You must set the tan_unit_111.txt file to be writable (check file name as also).
Erectile dysfunction
Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.
Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.
This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.
What is Erectile Dysfunction?
Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.
The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.
Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.
The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.
Signs and symptoms:
Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).
Here are some causes of Erectile Dysfunction:
* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.
* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.
* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.
Physiology of normal erections:
Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.
Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.
Pathophysiology of erectile dysfunction:
Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.
Treatment:
Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.
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