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What is fluconazole?

  • Fluconazole is an antifungal medication. It is used to treat fungal infections.
  • Fluconazole is used to treat yeast infections of the mouth, throat, and esophagus; vaginal yeast infections; fungal urinary tract infections; pneumonia caused by yeast; and fungal infections throughout the whole body and in the blood. Fluconazole is also used to prevent fungal infections from occurring in people with suppressed immune systems such as cancer chemotherapy patients, organ transplant patients, and AIDS patients.
  • Fluconazole may also be used for purposes other than those listed in this medication guide.

What should I discuss with my doctor before taking fluconazole?

  • Do not take fluconazole if you are taking cisapride (Propulsid). Combined with cisapride (Propulsid), fluconazole could cause serious, even fatal, heart problems.
  • Before taking fluconazole, tell your doctor if you have any other medical conditions, especially kidney disease, or if you take other medicines. You may not be able to take fluconazole, or you may require a dosage adjustment or special monitoring during your treatment.
  • Fluconazole is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take fluconazole without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • Fluconazole passes into breast milk and may be harmful to a nursing baby. For this reason, fluconazole should not be taken by nursing mothers. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take fluconazole?

  • Take fluconazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • A single dose of this medication is often used to treat vaginal yeast infections.
  • In multiple-dose therapy, a double dose of fluconazole is often taken on the first day of treatment to quickly get the proper amount of medicine into the body. Follow your doctor's directions.
  • Shake the suspension well before measuring a dose. To ensure that you get the correct dose, measure the suspension using a dose-measuring spoon, cup, or dropper, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
  • It is important to take fluconazole regularly to get the most benefit.
  • Store the tablets at room temperature away from moisture and heat.
  • The suspension can be stored at room temperature or in the refrigerator. Do not let it freeze. Throw away any unused suspension after 14 days.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

  • Seek emergency medical attention if an overdose is suspected.
  • Symptoms of a fluconazole overdose include confusion, hallucinations, paranoia, decreased movement, decreased breathing, tearing eyes, drooling, urinary incontinence, seizures, and death.

What should I avoid while taking fluconazole?

  • Avoid alcohol or use it in moderation while taking fluconazole. Alcohol and fluconazole can both affect the liver.
  • Use caution when driving or performing other hazardous activities. Fluconazole may cause dizziness. If you experience dizziness, avoid these activities.

What are the possible side effects of fluconazole?

  • If you experience any of the following serious side effects, stop taking fluconazole and seek emergency medical attention or contact your doctor immediately:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    • liver damage (pale stools, yellowing of the skin or eyes, abdominal pain, unusual fatigue, or dark urine); or
    • a rash.
  • Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue taking fluconazole and talk to your doctor:
    • nausea, vomiting, or abdominal pain;
    • diarrhea;
    • headache;
    • dizziness;
    • fatigue; or
    • itching.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What drug(s) may interact with ?

  • bosentan
  • cilostazol
  • cisapride
  • cyclosporine
  • dofetilide
  • doxercalciferol
  • certain medicines for anxiety or difficulty sleeping
  • medicines for diabetes that are taken by mouth
  • medicines for high cholesterol such as atorvastatin, fluvastatin, lovastatin, or simvastatin
  • medicines for yeast or fungal infections
  • paricalcitol
  • phenytoin
  • pimozide
  • ramelteon
  • rifabutin
  • rifampin
  • tacrolimus
  • terfenadine
  • warfarin
  • water pills

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Thank you for the complimentary pack of Sildenafil Citrate I'll be sure to put them to good use.

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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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