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What does the term "generic" mean? Do generic medications produce the same effect that the brand name medicines do?

The difference between a brand name medicine and a generic one is in the name, shape and in the price. A generic drug is usually called by the name of the active ingredient while a manufacturer uses a brand name. However, a manufacturer cannot possess a patent for a certain chemical agent, this is why manufacturers of generic medications can legally produce the so-called "generics". They are the same chemically and since the active ingredient is identical, they have the same medical effect. Thus buying a generic medication one pays less but gets the very same result.

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Carvedilol is used for:

Treating high blood pressure or certain types of heart failure. It may also be used after a heart attack to improve survival in certain patients. It may be used along with other medicines. It may also be used for other conditions as determined by your doctor.

Carvedilol is a beta-blocker. It works by relaxing the blood vessels, slowing down the heart, and decreasing the amount of blood it pumps out. This decreases blood pressure, helps the heart pump more efficiently, and reduces the workload on the heart.

Do NOT use Carvedilol if:

  • you are allergic to any ingredient in Carvedilol
  • you have moderate to severe heart block, sick sinus syndrome, very slow heartbeat (unless you have a permanent pacemaker), certain types of irregular heartbeat or severe heart failure, or shock caused by serious heart problems
  • you have asthma or other severe breathing problems
  • you have severe liver problems
  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Carvedilol :

Some medical conditions may interact with Carvedilol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances or are taking medicine for allergies
  • if you have a history of other heart problems (eg, heart failure, slow heartbeat, angina) or low blood pressure
  • if you have a history of liver or kidney problems, blood vessel disease, blood flow problems (eg, in the legs or feet), lung or breathing problems (eg, chronic bronchitis emphysema, chronic obstructive pulmonary disease), diabetes, low blood sugar, thyroid problems, or glaucoma
  • if you have an adrenal gland tumor (pheochromocytoma)
  • if you will be having surgery

Some MEDICINES MAY INTERACT with Carvedilol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Mibefradil because the risk of serious heart side effects may be increased
  • Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, heart problems, irregular heartbeat, diabetes, depression, mental or mood problems, immune system suppression, allergic reactions, asthma, high cholesterol, seizures), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may interact with Carvedilol , increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carvedilol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Carvedilol :

Use Carvedilol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Carvedilol by mouth with food.
  • Take Carvedilol on a regular schedule to get the most benefit from it.
  • Taking Carvedilol at the same time(s) each day will help you remember to take it.
  • Continue to use Carvedilol even if you feel well. Do not miss any doses.
  • Do not suddenly stop taking Carvedilol. You may have an increased risk of side effects. If you need to stop Carvedilol or add a new medicine, your doctor will gradually lower your dose.
  • If you miss a dose of Carvedilol , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carvedilol.

Important safety information:

  • Carvedilol may cause dizziness, fainting, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Carvedilol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Carvedilol may cause dizziness, lightheadedness, or fainting. These effects may occur within the first hour after you take your dose. They may be more likely when you start taking Carvedilol or if your dose is increased. Alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Tell your doctor if these effects occur.
  • Do NOT take more than the recommended dose without checking with your doctor.
  • Do not suddenly stop taking Carvedilol. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Carvedilol. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take Carvedilol for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Carvedilol again.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Tell your doctor or dentist that you take Carvedilol before you receive any medical or dental care, emergency care, or surgery.
  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk for an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Carvedilol .
  • Diabetes patients - Carvedilol may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Diabetes patients - Carvedilol may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including blood pressure and heart function, may be performed while you use Carvedilol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Carvedilol with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness.
  • Carvedilol should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Carvedilol while you are pregnant. It is not known if Carvedilol is found in breast milk. Do not breast-feed while taking Carvedilol.

Possible side effects of Carvedilol :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; dry eyes; headache; fatigue; lightheadedness; nausea; numbness or tingling of the hands or feet; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine produced; chest pain; disorientation; fainting; fever; irregular or unusually slow heartbeat; persistent or severe vision changes; severe dizziness; shortness of breath; sudden unusual weight gain; swelling of the hands, ankles, or feet; unusual bruising or bleeding.

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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