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Clomiphene is used for:
Treating female infertility and forcertain conditions as determined by your doctor.
Clomiphene is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release 1 or more eggs.
Do NOT use Clomiphene if:
you are allergic to any ingredient in Clomiphene
you are pregnant
you have abnormal vaginal bleeding
you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome
you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body
you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (eg, pituitary gland tumor)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Clomiphene :
Some medical conditions may interact with Clomiphene. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are planning to become pregnant or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have depression, endometriosis, polycystic ovarian syndrome, or uterine fibroids
Some MEDICINES MAY INTERACT with Clomiphene. However, no specific interactions with Clomiphene are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Clomiphene may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Clomiphene :
Use Clomiphene as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Clomiphene may be taken with or without food.
Properly timed sexual intercourse is important for good results. Ovulation usually occurs 5 to 10 days after a dose of Clomiphene.
If pregnancy has not been successful after 3 courses of treatment, further treatment is not recommended. Long-term use of Clomiphene is not recommended.
If you miss a dose of Clomiphene , contact your doctor for instructions.
Ask your health care provider any questions you may have about how to use Clomiphene.
Important safety information:
Clomiphene may cause dizziness, lightheadedness, or vision disturbances, including blurring, spots, and flashes. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Clomiphene. Using Clomiphene alone, with certain other medicines, or with
alcohol may lessen your ability to drive or perform other potentially
dangerous tasks.
Enlargement of the ovaries may happen during or shortly after taking Clomiphene. Call your health care provider if you experience any stomach or pelvic pain, weight gain, pain, or stomach enlargement or discomfort while taking Clomiphene.
LAB TESTS, including pregnancy tests, will be needed while you are taking Clomiphene. Be sure to keep all doctor and lab appointments.
Use Clomiphene with caution in the ELDERLY because they may be more sensitive to its effects.
Clomiphene is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
Pregnancy with more than 1 fetus (eg, twins) is possible while you are taking Clomiphene. Be sure you have discussed the potential complications and hazards of multiple pregnancy.
PREGNANCY and BREAST-FEEDING: Do not use Clomiphene if you are or become pregnant. If you suspect that you could be pregnant, contact your doctor; it is important to not take Clomiphene while pregnant. It is unknown if Clomiphene is excreted in breast milk. Do not breast-feed while taking
Clomiphene.
Possible side effects of Clomiphene :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Blurred vision or vision problems (spots or flashes); breast tenderness; dizziness; enlarged breasts; enlargement of the ovaries; flushing; headache; hot flashes; lightheadedness; mood change; nausea; pelvic pain or bloating; stomach pain; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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Erectile dysfunction
Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.
Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.
This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.
What is Erectile Dysfunction?
Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.
The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.
Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.
The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.
Signs and symptoms:
Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).
Here are some causes of Erectile Dysfunction:
* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.
* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.
* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.
Physiology of normal erections:
Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.
Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.
Pathophysiology of erectile dysfunction:
Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.
Treatment:
Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.
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