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What is desloratadine?

  • Desloratadine is an antihistamine. Antihistamines prevent sneezing, runny nose, itching and watering of the eyes, and other allergic symptoms.
  • Desloratadine is used to treat the symptoms of allergies.
  • Desloratadine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about desloratadine?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Although unlikely, desloratadine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

What should I discuss with my healthcare provider before taking desloratadine?

  • Before taking desloratadine, tell your doctor if you have
    • ever had an allergic reaction to an antihistamine;
    • kidney disease; or
    • liver disease.
  • You may not be able to take desloratadine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
  • Desloratadine is in the FDA pregnancy category C. This means that it is not known whether desloratadine will be harmful to an unborn baby. Do not take desloratadine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Desloratadine passes into breast milk and may affect a nursing infant. Do not take desloratadine without first talking to your doctor if you are breast-feeding a baby.

How should I take desloratadine?

  • Take desloratadine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each regular tablet with a full glass (8 ounces) of water.
  • Place a desloratadine orally-disintegrating-tablets (Clarinex Reditabs) on the tongue and allow it dissolve. The tablet will disintegrate rapidly. Swallow with or without water. Take the desloratadine orally-disintegrating tablets immediately after removal from the blister packaging. Do not store for later use.
  • Desloratadine can be taken with or without food.
  • Desloratadine is usually taken once a day. Follow your doctor's instructions.
  • Never take more of this medication than directed. If your symptoms do not improve, talk to your doctor.
  • Store desloratadine at room temperature away from moisture and heat. Avoid exposing the medication to temperatures above 86 degrees Fahrenheit (30 degrees Celsius ).

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

  • Seek emergency medical attention if an overdose is suspected.
  • Symptoms of a desloratadine overdose are not well known but may include drowsiness.

What should I avoid while taking desloratadine?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Although unlikely, desloratadine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Desloratadine side effects

  • If you experience any of the following rare but serious side effects, stop taking desloratadine and contact your doctor immediately or seek emergency medical attention.
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
    • irregular or fast heartbeats.
  • Other, less serious side effects may be more likely to occur. Continue to take desloratadine and talk to your doctor if you experience
    • drowsiness or dizziness;
    • nausea;
    • dry mouth or throat; or
    • muscle aches.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect desloratadine?

  • There are no known interactions between desloratadine and other medications. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, during treatment with desloratadine.

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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