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Cialis Basics

Author: Tia Arora

Article source: http://genericviagra.blogster.com/. Used with author's permission.

Introduction
Sex has been the part of the life since the day Adam saw the apple. Man has been striving to achieve a better performance in order to satisfy both his as well his partner's requirements. Age, hormonal imbalances, society, money and many other things have not been able to remain a barrier for long in this quest. Medicinal herbs, fruits and certain exercises such as meditation have helped him in one way or the other but there has always been a search to help men in his erectile dysfunction in nearly all cases with having minimum of the side effects. Viagra hit the market in 1998 and was an instant success in that regard. But due to its side effects more research was still needed and a new product was about to come. Cialis then came and with its minimum side effects profile and the greater half-life was what people needed the most.

What is erectile dysfunction?
Erectile dysfunction is the inability of the person to either initiate or sustain a penile erection for a sufficient period of time that is needed to attain a sexual gratification. The causes of it may be many for e.g. psychological, hormonal, arterial or muscular. The diseases associated with it are Diabetes Mellitus, Major Depression, certain thrombotic disorders, etc.

What is Cialis?

Cialis and drugs related to it like Viagra act by inhibiting an enzyme called phosphodiesterase type 5 which release Nitric Oxide from nerve endings and endothelium causing relaxation of smooth muscle and hence penile erection. This is a product developed by Eli Lilly and ICOS and it is a trade name of the product called Tadalafil launched in the market in 2003.

What are the advantages and side effects?
Although the vasodilatation that is needed is in penis, due to the extreme non-specificity of the product there are certain side effects related to vasodilatation at other sites such as headache, nasal congestion, stuffiness, and fall in blood pressure. Some patients complain of loose motions. These side effects are more applicable to products such as Viagra than to Cialis. Some patients have suffered heart attack and severe fall in blood pressure.

Who all can benefit?
Men with erectile dysfunction due to some arterial disorders will benefit the most. It doesn't benefit those with hormonal problems or psychological problems except those with Diabetic neuropathy. There is a myth that a person as soon as taking the drug will have erection but that is not the case. It starts taking action only when a person starts physical activity.

How is Cialis better than others?
Cialis has a half life of around 36 hours while that of Viagra is around 4 hours that means that a person can take the drug and can expect to have erection at a time much later than the time of administration. This achieves much patient compliance.

What is the latest research that is going on?
The latest research that is going on is hormonal therapy and genetic therapy in this regard. These are basically to avoid the side effect profile of these type of drugs.

Tia arora writes Cialis basics topics. Learn more at http://www.cialislifestyle.com.


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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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