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The shipping rates vary depending on the shipping type you choose and on the country of the destination. Please check the table below:

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Nifedipine is used for:

Treating certain kinds of angina (chest pain). It may also be used for other conditions as determined by your doctor.

Nifedipine is a calcium channel blocking agent. It works by interfering with the normal action of calcium in blood vessel constriction (relaxes the blood vessels) and heart muscle contraction (heart may beat with less force and pump out less blood) and nerve conduction in the heart (heart may beat more slowly and more regularly). Calcium channel blockers are used to dilate (widen) the arteries of the heart and other arteries (reduce angina chest pain and reduce elevated blood pressure), and stabilize the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm (antiarrhythmic effects).

Its main uses are in angina pectoris (especially Prinzmetal's angina) and hypertension, although a large number of other uses have recently been found for this agent, such as Raynaud's phenomenon, premature labor, and painful spasms of the esophagus in cancer and tetanus patients.

Do NOT use Nifedipine if:

  • you are allergic to any ingredient in Nifedipine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nifedipine :

Some medical conditions may interact with Nifedipine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart valve problems, heart failure, heart shock, heart disease, had a heart attack, swelling of the hands or feet, a slow heart rate, low blood pressure, or fluid in your lungs
  • if you have recently had or will be having surgery, or if you have recently stopped taking a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Nifedipine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, or rifampin because they may decrease Nifedipine 's effectiveness
  • Beta-blockers (eg, propranolol), cimetidine, cyclosporine, fluconazole, fluoxetine, imatinib, itraconazole, ketanserin, magnesium salts (eg, injectable magnesium sulfate), quinazolines (eg, metolazone), quinidine, or ranitidine because side effects, including very low blood pressure, may occur
  • Beta-blockers (eg, propranolol), cyclosporine, digoxin, hydantoins (eg, phenytoin), ketanserin, lithium, theophylline, vinca alkaloids (eg, vincristine) because the actions and side effects of these medicines may be increased
  • Quinidine, theophylline, or vinca alkaloids (eg, vincristine) because their effectiveness may be decreased by Nifedipine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nifedipine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nifedipine :

Use Nifedipine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Nifedipine by mouth with or without food.
  • Do not eat grapefruit or drink grapefruit juice while you use Nifedipine.
  • Swallow Nifedipine whole. Do not break, crush, or chew before swallowing.
  • If you miss a dose of Nifedipine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nifedipine.

Important safety information:

  • Nifedipine may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Nifedipine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Proper dental care is important while you are taking Nifedipine. Brush and floss your teeth and visit the dentist regularly.
  • Use Nifedipine with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nifedipine while you are pregnant. It is not known if Nifedipine is found in breast milk. If you are or will be breast-feeding while you use Nifedipine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Nifedipine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; flushing; giddiness; headache; heat sensation; heartburn; lightheadedness; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irregular pulse; shortness of breath; swelling of the feet or hands; tender, bleeding, or swollen gums.

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

I already received my parcel, I had a problem as the courier wanted to deliver to my home as they claim they cannot place the order into my postbox. This was my preferred option.
There is not someone at home always, so we had to get the parcel to my office. No problem with that.
I did have an enquiry into the 4 extra pills, and this was delivered within a few days via airmail to my post box.
I would suggest you attend to this part of your process as the extra cost is unnecessary. Include everything into one parcel.
All in all, good service. - Jan

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Erectile dysfunction

Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity. Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.

Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.

This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.

What is Erectile Dysfunction?

Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.

The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.

Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.

The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.

Signs and symptoms:

Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).

Here are some causes of Erectile Dysfunction:

* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.

* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.

* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.

Physiology of normal erections:

Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.

Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.

Pathophysiology of erectile dysfunction:

Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.

Treatment:

Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.

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